A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole.

Protein transport in eukaryotic cells requires the selective docking and fusion of transport intermediates with the suitable goal membrane. t-SNARE molecules which can be related to distinct intracellular compartments could function receptors for transport vesicle docking and membrane fusion by means of interactions with particular v-SNARE molecules on vesicle membranes, offering the inherent specificity of those reactions. VAM3 encodes a 283-amino acid protein that shares homology with the syntaxin household of t-SNARE molecules. Polyclonal antiserum raised in […]